{"id":33417,"date":"2019-11-13T02:30:12","date_gmt":"2019-11-13T00:30:12","guid":{"rendered":"https:\/\/naturopatiadigital.eu\/?p=33417"},"modified":"2019-11-13T02:30:12","modified_gmt":"2019-11-13T00:30:12","slug":"area-de-conocimiento-naturopatia-descriptiva-obesidad-inflamacion-y-enfermedad-vascular-el-papel-del-tejido-adiposo-como-organo-endocrino","status":"publish","type":"post","link":"https:\/\/rina.naturopatiadigital.eu\/?p=33417","title":{"rendered":"\u00c1rea de conocimiento: Naturopat\u00eda Descriptiva: \u00abObesidad, inflamaci\u00f3n y enfermedad vascular: el papel del tejido adiposo como \u00f3rgano endocrino\u00bb"},"content":{"rendered":"

<\/a>Calabro, P., & Yeh, E. T. (2007).\u00a0Obesity, Inflammation, and Vascular Disease<\/a>. In Inflammation in the Pathogenesis of Chronic Diseases<\/i>\u00a0(pp. 63-91). Springer, Dordrecht.<\/p>\n

La resistencia a la insulina, tanto en sujetos no diab\u00e9ticos como diab\u00e9ticos, se asocia frecuentemente con la obesidad, particularmente con un exceso de grasa central. Con la creciente prevalencia de la obesidad, el inter\u00e9s cient\u00edfico en la biolog\u00eda del tejido adiposo se ha extendido a los productos secretores de los adipocitos, ya que cada vez se ha demostrado que influyen en varios aspectos en la patog\u00e9nesis de las enfermedades relacionadas con la obesidad\u00a0<\/p>\n

Hasta hace relativamente poco, el papel de la grasa en el desarrollo de la obesidad y sus consecuencias se consider\u00f3 pasiva; se consider\u00f3 que los adipocitos eran poco m\u00e1s que c\u00e9lulas de almacenamiento de grasa. Ahora est\u00e1 claro que, adem\u00e1s de almacenar calor\u00edas como triglic\u00e9ridos, tambi\u00e9n secretan una gran variedad de prote\u00ednas, incluidas citocinas, quimiocinas y factores similares a las hormonas, como leptina, adiponectina y resistina. Esta producci\u00f3n de quimiocinas pro-aterog\u00e9nicas por tejido adiposo es de particular inter\u00e9s ya que su secreci\u00f3n local, por ejemplo, por dep\u00f3sitos adiposos perivasculares, puede proporcionar un nuevo v\u00ednculo mecanicista entre la obesidad y las complicaciones vasculares asociadas.\u00a0<\/p>\n

Investigaciones recientes han revelado muchas funciones de las adipocitocinas que se extienden mucho m\u00e1s all\u00e1 del metabolismo, como la inmunidad, el c\u00e1ncer y la formaci\u00f3n de huesos. Esta notable comprensi\u00f3n nos permite definir m\u00e1s claramente el papel que juegan los adipocitos en la salud y la obesidad y c\u00f3mo los mediadores inflamatorios act\u00faan como mol\u00e9culas de se\u00f1alizaci\u00f3n en este proceso. Adem\u00e1s, a nivel molecular, estamos comenzando a comprender c\u00f3mo interact\u00faan las variables como el control hormonal, el ejercicio, la ingesta de alimentos y la variaci\u00f3n gen\u00e9tica y dan como resultado un fenotipo dado, y c\u00f3mo la intervenci\u00f3n farmacol\u00f3gica puede modular la biolog\u00eda del tejido adiposo.<\/p>\n","protected":false},"excerpt":{"rendered":"

Calabro, P., & Yeh, E. T. (2007).\u00a0Obesity, Inflammation, and Vascular Disease. In Inflammation in the Pathogenesis of Chronic Diseases\u00a0(pp. 63-91). Springer, Dordrecht. La resistencia a la insulina, tanto en sujetos no diab\u00e9ticos como diab\u00e9ticos, se asocia frecuentemente con la obesidad, particularmente con un exceso de grasa central. Con la creciente prevalencia de la obesidad, el […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[9],"tags":[],"class_list":["post-33417","post","type-post","status-publish","format-standard","hentry","category-naturopatia-descriptiva"],"yoast_head":"\n\u00c1rea de conocimiento: Naturopat\u00eda Descriptiva: "Obesidad, inflamaci\u00f3n y enfermedad vascular: el papel del tejido adiposo como \u00f3rgano endocrino" -<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/rina.naturopatiadigital.eu\/?p=33417\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u00c1rea de conocimiento: Naturopat\u00eda Descriptiva: "Obesidad, inflamaci\u00f3n y enfermedad vascular: el papel del tejido adiposo como \u00f3rgano endocrino" -\" \/>\n<meta property=\"og:description\" content=\"Calabro, P., & Yeh, E. T. (2007).\u00a0Obesity, Inflammation, and Vascular Disease. In Inflammation in the Pathogenesis of Chronic Diseases\u00a0(pp. 63-91). Springer, Dordrecht. La resistencia a la insulina, tanto en sujetos no diab\u00e9ticos como diab\u00e9ticos, se asocia frecuentemente con la obesidad, particularmente con un exceso de grasa central. 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