{"id":34495,"date":"2019-12-12T06:30:21","date_gmt":"2019-12-12T05:30:21","guid":{"rendered":"https:\/\/naturopatiadigital.eu\/?p=34495"},"modified":"2019-12-12T06:30:21","modified_gmt":"2019-12-12T05:30:21","slug":"area-de-conocimiento-tecnologia-naturopatica-o-naturopatia-aplicada-modulo-naturopatia-funcionalmodulacion-de-la-respuesta-inflamatoria-a-la-leishmaniosis-cutanea-murina-por-medicamentos-homeopati","status":"publish","type":"post","link":"https:\/\/rina.naturopatiadigital.eu\/?p=34495","title":{"rendered":"\u00c1rea de conocimiento: Tecnolog\u00eda Naturop\u00e1tica o Naturopat\u00eda Aplicada: M\u00f3dulo: Naturopat\u00eda Funcional: \u00abModulaci\u00f3n de la respuesta inflamatoria a la leishmaniosis cut\u00e1nea murina por medicamentos homeop\u00e1ticos: timulina 5cH\u00bb"},"content":{"rendered":"

<\/a>De Santana, F. R., de Paula Coelho, C., Cardoso, T. N., Laurenti, M. D., Hurtado, E. C. P., & Bonamin, L. V. (2014).\u00a0Modulation of inflammation response to murine cutaneous Leishmaniosis by homeopathic medicines: Thymulin 5cH<\/a>.\u00a0Homeopathy<\/i>, 103(04), 275-284.<\/p>\n

FONDO: En estudios previos, observamos que la timulina 5cH podr\u00eda modular la inflamaci\u00f3n cr\u00f3nica inducida por BCG (Bacillus Calmette-Guerin) al aumentar la diferenciaci\u00f3n de c\u00e9lulas madre B1 peritoneales en fagocitos y mejorar la eficiencia de la fagocitosis.<\/p>\n

M\u00c9TODOS: Utilizamos el mismo protocolo para estudiar los efectos de la timulina 5cH en la leishmaniasis murina experimental, con el fin de dilucidar algunos aspectos de la relaci\u00f3n par\u00e1sito-hu\u00e9sped bajo este tratamiento homeop\u00e1tico. Los ratones macho Balb \/ c se trataron oralmente con timulina 5cH o veh\u00edculo durante 60 d\u00edas, despu\u00e9s de la inoculaci\u00f3n subcut\u00e1nea de 2 x 10 (6) unidades de Leishmania (L.) amazonensis en la almohadilla del pie. La suspensi\u00f3n de c\u00e9lulas inflamatorias lavadas de la cavidad peritoneal, el bazo, los ganglios linf\u00e1ticos locales y el tejido subcut\u00e1neo infectado se cosecharon despu\u00e9s de 2 y 60 d\u00edas de la infecci\u00f3n para cuantificar las c\u00e9lulas de inflamaci\u00f3n mediante m\u00e9todos de citometr\u00eda de flujo e histometr\u00eda.<\/p>\n

RESULTADOS: Despu\u00e9s de un aumento transitorio de las c\u00e9lulas T reg peritoneales, los ratones tratados presentaron, cr\u00f3nicamente, un aumento en el porcentaje de c\u00e9lulas B1 peritoneales y del bazo (p = 0,0001) en relaci\u00f3n con otros tipos de c\u00e9lulas; respuesta de inflamaci\u00f3n m\u00e1s organizada y exuberante en el sitio de infecci\u00f3n, y disminuci\u00f3n en el n\u00famero de par\u00e1sitos por campo dentro de la lesi\u00f3n primaria (p = 0.05). No se observaron diferencias en la histolog\u00eda local de los ganglios linf\u00e1ticos.<\/p>\n

CONCLUSIONES: La timulina 5cH puede mejorar la activaci\u00f3n de las c\u00e9lulas B1 y la eficacia de la fagocitosis de amazonensis de Leishmania (L) en ratones, de manera similar a la observada previamente en la infecci\u00f3n experimental con BCG.<\/p>\n","protected":false},"excerpt":{"rendered":"

De Santana, F. R., de Paula Coelho, C., Cardoso, T. N., Laurenti, M. D., Hurtado, E. C. P., & Bonamin, L. V. (2014).\u00a0Modulation of inflammation response to murine cutaneous Leishmaniosis by homeopathic medicines: Thymulin 5cH.\u00a0Homeopathy, 103(04), 275-284. FONDO: En estudios previos, observamos que la timulina 5cH podr\u00eda modular la inflamaci\u00f3n cr\u00f3nica inducida por BCG (Bacillus […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[30],"tags":[],"class_list":["post-34495","post","type-post","status-publish","format-standard","hentry","category-investigaciones-naturopatica-nfu"],"yoast_head":"\n\u00c1rea de conocimiento: Tecnolog\u00eda Naturop\u00e1tica o Naturopat\u00eda Aplicada: M\u00f3dulo: Naturopat\u00eda Funcional: "Modulaci\u00f3n de la respuesta inflamatoria a la leishmaniosis cut\u00e1nea murina por medicamentos homeop\u00e1ticos: timulina 5cH" -<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/rina.naturopatiadigital.eu\/?p=34495\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u00c1rea de conocimiento: Tecnolog\u00eda Naturop\u00e1tica o Naturopat\u00eda Aplicada: M\u00f3dulo: Naturopat\u00eda Funcional: "Modulaci\u00f3n de la respuesta inflamatoria a la leishmaniosis cut\u00e1nea murina por medicamentos homeop\u00e1ticos: timulina 5cH" -\" \/>\n<meta property=\"og:description\" content=\"De Santana, F. R., de Paula Coelho, C., Cardoso, T. N., Laurenti, M. D., Hurtado, E. C. P., & Bonamin, L. V. (2014).\u00a0Modulation of inflammation response to murine cutaneous Leishmaniosis by homeopathic medicines: Thymulin 5cH.\u00a0Homeopathy, 103(04), 275-284. 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