{"id":43042,"date":"2020-07-18T04:30:05","date_gmt":"2020-07-18T02:30:05","guid":{"rendered":"https:\/\/rina.naturopatiadigital.eu\/?p=43042"},"modified":"2020-07-19T19:55:55","modified_gmt":"2020-07-19T17:55:55","slug":"43042","status":"publish","type":"post","link":"https:\/\/rina.naturopatiadigital.eu\/?p=43042","title":{"rendered":"\u00c1rea de conocimiento: Naturopat\u00eda Experimental: Sustancias Bioactivas: \u00abFitopolifenoles como posibles inhibidores de met\u00e1stasis de c\u00e1ncer de mama\u00bb"},"content":{"rendered":"

<\/a>Avtanski, D., & Poretsky, L. (2018).\u00a0Phyto-polyphenols as potential inhibitors of breast cancer metastasis<\/a>.\u00a0Molecular Medicine<\/i>, 24(1), 29.<\/p>\n

El c\u00e1ncer de mama es el c\u00e1ncer m\u00e1s com\u00fan entre las mujeres, ya que la met\u00e1stasis es actualmente la principal causa de mortalidad. Las c\u00e9lulas de c\u00e1ncer de mama que sufren met\u00e1stasis adquieren resistencia a las se\u00f1ales de muerte y al aumento de la motilidad celular y la invasividad.<\/p>\n

Las plantas son ricas en compuestos polifen\u00f3licos, muchos de ellos con efectos medicinales conocidos. Tambi\u00e9n se ha demostrado que varios fitopolifenoles suprimen el crecimiento del c\u00e1ncer. Su mecanismo de acci\u00f3n suele ser pleiotr\u00f3pico, ya que se dirigen a m\u00faltiples v\u00edas de se\u00f1alizaci\u00f3n que regulan procesos celulares clave como la proliferaci\u00f3n, la apoptosis y la diferenciaci\u00f3n. Es importante destacar que algunos fitopolifenoles muestran un bajo nivel de toxicidad para las c\u00e9lulas no transformadas, pero efectos selectivos de supresi\u00f3n sobre la proliferaci\u00f3n y diferenciaci\u00f3n de las c\u00e9lulas cancerosas.<\/p>\n

En esta revisi\u00f3n, resumimos la informaci\u00f3n actual sobre el mecanismo de acci\u00f3n de algunos fitopolifenoles que han demostrado actividades anticancer\u00edgenas in vitro e in vivo. El conocimiento adquirido de c\u00f3mo funcionan estos compuestos polifen\u00f3licos naturales puede darnos una pista para el desarrollo de nuevos agentes antimetast\u00e1sicos.<\/p>\n","protected":false},"excerpt":{"rendered":"

Avtanski, D., & Poretsky, L. (2018).\u00a0Phyto-polyphenols as potential inhibitors of breast cancer metastasis.\u00a0Molecular Medicine, 24(1), 29. El c\u00e1ncer de mama es el c\u00e1ncer m\u00e1s com\u00fan entre las mujeres, ya que la met\u00e1stasis es actualmente la principal causa de mortalidad. Las c\u00e9lulas de c\u00e1ncer de mama que sufren met\u00e1stasis adquieren resistencia a las se\u00f1ales de muerte […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[8],"tags":[],"class_list":["post-43042","post","type-post","status-publish","format-standard","hentry","category-sustancias-bioactivas"],"yoast_head":"\n\u00c1rea de conocimiento: Naturopat\u00eda Experimental: Sustancias Bioactivas: "Fitopolifenoles como posibles inhibidores de met\u00e1stasis de c\u00e1ncer de mama" -<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/rina.naturopatiadigital.eu\/?p=43042\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u00c1rea de conocimiento: Naturopat\u00eda Experimental: Sustancias Bioactivas: "Fitopolifenoles como posibles inhibidores de met\u00e1stasis de c\u00e1ncer de mama" -\" \/>\n<meta property=\"og:description\" content=\"Avtanski, D., & Poretsky, L. (2018).\u00a0Phyto-polyphenols as potential inhibitors of breast cancer metastasis.\u00a0Molecular Medicine, 24(1), 29. El c\u00e1ncer de mama es el c\u00e1ncer m\u00e1s com\u00fan entre las mujeres, ya que la met\u00e1stasis es actualmente la principal causa de mortalidad. Las c\u00e9lulas de c\u00e1ncer de mama que sufren met\u00e1stasis adquieren resistencia a las se\u00f1ales de muerte […]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/rina.naturopatiadigital.eu\/?p=43042\" \/>\n<meta property=\"article:published_time\" content=\"2020-07-18T02:30:05+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2020-07-19T17:55:55+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/1.bp.blogspot.com\/-I9_rV8ecdBU\/XxSHhlH-YLI\/AAAAAAAAeg0\/XKKI7D6cKbI3OetVnP10b4WnMNReLFSqwCLcBGAsYHQ\/s320\/Molecular_Medicine.JPG\" \/>\n<meta name=\"author\" content=\"admin\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Escrito por\" \/>\n\t<meta name=\"twitter:data1\" content=\"admin\" \/>\n\t<meta name=\"twitter:label2\" content=\"Tiempo de lectura\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minuto\" \/>\n<script type=\"application\/ld+json\" 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