{"id":45926,"date":"2022-07-29T16:27:31","date_gmt":"2022-07-29T14:27:31","guid":{"rendered":"https:\/\/RevistaEspa\u00f1oladeNaturopatia.naturopatiadigital.eu\/?p=45926"},"modified":"2022-07-29T16:27:31","modified_gmt":"2022-07-29T14:27:31","slug":"area-de-conocimiento-tecnologia-naturopatica-o-naturopatia-aplicada-modulo-naturopatia-fitocomplementaria-herbologia-inhibicion-de-la-osteoclastogenesis-humana-in-vitro-por-equisetum","status":"publish","type":"post","link":"https:\/\/rina.naturopatiadigital.eu\/?p=45926","title":{"rendered":"\u00c1rea de conocimiento: Tecnolog\u00eda Naturop\u00e1tica o Naturopat\u00eda Aplicada: M\u00f3dulo: Naturopat\u00eda Fitocomplementaria \u2013 HERBOLOGIA: \u00bb Inhibici\u00f3n de la osteoclastog\u00e9nesis humana in vitro por Equisetum arvense\u00bb"},"content":{"rendered":"

\"\"Costa\u2010Rodrigues, J., Carmo, S. C., Silva, J. C., & Fernandes, M. H. R. (2012). Inhibition of human in vitro osteoclastogenesis by E quisetum arvense<\/a>.\u00a0Cell proliferation<\/i>,\u00a045<\/i>(6), 566-576.<\/p>\n

\n

OBJETIVO: E\u00a0quisetum arvense<\/em>\u00a0se ha utilizado durante mucho tiempo en la medicina tradicional para tratar diferentes trastornos, incluidas las patolog\u00edas \u00f3seas.\u00a0En este estudio se utiliz\u00f3 un extracto hidrometan\u00f3lico de\u00a0E\u00a0.\u00a0arvense<\/em>\u00a0fue evaluado por sus efectos sobre la osteoclastog\u00e9nesis humana.<\/p>\n<\/div>\n

\n

MATERIALES Y METODO: Los precursores de osteoclastos se mantuvieron en condiciones no estimuladas y estimuladas (presencia de <\/span>M\u2010CSF<\/span>\u00a0y\u00a0<\/span>RANKL<\/span>\u00a0), o en cocultivos con osteoblastos.\u00a0Los cultivos celulares se trataron con 0,00016-0,5 mg\/ml de una\u00a0<\/span>E<\/span>\u00a0.\u00a0<\/span><\/em>extracto\u00a0de arvense<\/em><\/span><\/p>\n<\/div>\n

\n

RESULTADOS: El extracto no afect\u00f3 la osteoclastog\u00e9nesis espont\u00e1nea. En precursores de osteoclastos comprometidos con la osteoclastog\u00e9nesis (estimulados o cocultivados con osteoblastos), <\/span>E<\/span>\u00a0.\u00a0arvense<\/span><\/em>\u00a0caus\u00f3 un efecto inhibidor dependiente de la dosis que se volvi\u00f3 estad\u00edsticamente significativo en concentraciones \u22650,004 mg\/ml.\u00a0Esto se observ\u00f3 usando diferentes marcadores de activaci\u00f3n y diferenciaci\u00f3n de osteoclastos.\u00a0La respuesta celular se asoci\u00f3 con cambios en la contribuci\u00f3n relativa de las v\u00edas de se\u00f1alizaci\u00f3n de\u00a0<\/span>MEK<\/span>\u00a0y\u00a0<\/span>NFkB<\/span>\u00a0, as\u00ed como con la producci\u00f3n de\u00a0<\/span>PGE<\/span> 2. Como hubo diferencias en la respuesta de los precursores de osteoclastos mantenidos en presencia de factores inductivos, o cocultivados con c\u00e9lulas osteobl\u00e1sticas, parece que el extracto de <\/span>E<\/span> . arvense<\/span><\/em>\u00a0ten\u00eda la capacidad de modular la osteoclastog\u00e9nesis, ya sea actuando directamente sobre las c\u00e9lulas precursoras de osteoclastos y\/o\u00a0<\/span>a trav\u00e9s de los osteoblastos.<\/span><\/p>\n<\/div>\n

\n

CONCLUSIONES: Equisetum<\/span>\u00a0pareci\u00f3<\/span><\/em>\u00a0tener un efecto negativo sobre la osteoclastog\u00e9nesis humana, lo que est\u00e1 en consonancia con su supuesto papel beneficioso en las condiciones fisiopatol\u00f3gicas asociadas con una mayor actividad osteocl\u00e1stica, y podr\u00eda sugerir una utilidad potencial para el tratamiento con estrategias de regeneraci\u00f3n \u00f3sea.<\/span><\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Costa\u2010Rodrigues, J., Carmo, S. C., Silva, J. C., & Fernandes, M. H. R. (2012). Inhibition of human in vitro osteoclastogenesis by E quisetum arvense.\u00a0Cell proliferation,\u00a045(6), 566-576. OBJETIVO: E\u00a0quisetum arvense\u00a0se ha utilizado durante mucho tiempo en la medicina tradicional para tratar diferentes trastornos, incluidas las patolog\u00edas \u00f3seas.\u00a0En este estudio se utiliz\u00f3 un extracto hidrometan\u00f3lico de\u00a0E\u00a0.\u00a0arvense\u00a0fue evaluado […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5],"tags":[],"class_list":["post-45926","post","type-post","status-publish","format-standard","hentry","category-naturopatia-fitocomplementaria-herbologia"],"yoast_head":"\n\u00c1rea de conocimiento: Tecnolog\u00eda Naturop\u00e1tica o Naturopat\u00eda Aplicada: M\u00f3dulo: Naturopat\u00eda Fitocomplementaria \u2013 HERBOLOGIA: " Inhibici\u00f3n de la osteoclastog\u00e9nesis humana in vitro por Equisetum arvense" -<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/rina.naturopatiadigital.eu\/?p=45926\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u00c1rea de conocimiento: Tecnolog\u00eda Naturop\u00e1tica o Naturopat\u00eda Aplicada: M\u00f3dulo: Naturopat\u00eda Fitocomplementaria \u2013 HERBOLOGIA: " Inhibici\u00f3n de la osteoclastog\u00e9nesis humana in vitro por Equisetum arvense" -\" \/>\n<meta property=\"og:description\" content=\"Costa\u2010Rodrigues, J., Carmo, S. C., Silva, J. C., & Fernandes, M. H. R. (2012). Inhibition of human in vitro osteoclastogenesis by E quisetum arvense.\u00a0Cell proliferation,\u00a045(6), 566-576. OBJETIVO: E\u00a0quisetum arvense\u00a0se ha utilizado durante mucho tiempo en la medicina tradicional para tratar diferentes trastornos, incluidas las patolog\u00edas \u00f3seas.\u00a0En este estudio se utiliz\u00f3 un extracto hidrometan\u00f3lico de\u00a0E\u00a0.\u00a0arvense\u00a0fue evaluado […]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/rina.naturopatiadigital.eu\/?p=45926\" \/>\n<meta property=\"article:published_time\" content=\"2022-07-29T14:27:31+00:00\" \/>\n<meta name=\"author\" content=\"admin\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Escrito por\" \/>\n\t<meta name=\"twitter:data1\" content=\"admin\" \/>\n\t<meta name=\"twitter:label2\" content=\"Tiempo de lectura\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutos\" \/>\n<script type=\"application\/ld+json\" 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